ABO_ORCID ID: https://orcid.org/0000-0002-5233-9466, Scopus ID: 6602628612, WOS ID: ELB-1090-2022

2022 Int. J. Mol. Sci. 23, 14295 (pdf, suppl, figure) Zlacká, J.; Murár, M.; Addová, G.; Moravčík, R.; Boháč, A.; Zeman, M.; Synthesis of Glycolysis Inhibitor PFK15 and Its Synergistic Action with an Ap;proved Multikinase Antiangiogenic Drug on Human Endothelial Cell Migration and Proliferation. https://doi.org/10.3390/ijms232214295
2022 Chem Papers 76 6783-6788 (pdf) Bodo, P., Kovacikova, L., Bohac, A.,Stefek, M.; Cu(II) mediated oxidation of cemtirestat yields its disulfide under physiological conditions in vitro.
https://doi.org/10.1007/s11696-022-02368-w
2022 Medzinárodný patent WO 2022/132058 A1 (zverejnené 23.06.2022, link) M. Štefek, L. Kováčiková, M. Šoltésová Prnová, G. Addová, A. Boháč; Cemtirestat disulfide, prodrug of aldo-keto reductase inhibitor, preparation, pharmaceutical composition and use thereof.
2022 Slovenský patent PP 50074-2020 (zverejnené 30.06.2022 vo Vestníku úradu priem. vlastníctva (ÚPV SR) č. 12/2022, link), M. Štefek, L. Kováčiková, M. Šoltésová Prnová, G. Addová, A. Boháč; Cemtirestat disulfide, prodrug of aldo-keto reductase inhibitor, preparation, pharmaceutical composition and use thereof. (prihláška bola podaná 14.12.2020 PP 50074-2020)

M. Štefek, L. Kováčiková, M. Šoltésová P rnová, G. Addová, A. Boháč Zlúčenina cemtirestat disulfid, prekurzor inhibítora aldoketoreduktáz, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom a jeho použitie: dátum podania prihlášky: 14.12.2020. Banská Bystrica : Úrad priemyselného vlastníctva Slovenskej republiky, 2020. 25 s. Typ: AGJ web zaznam, pdf web zaznamu,
2021 Albert Schweitzer pice (PhD MH, Strasbourg 18.11.2021) - a picture
2021 Int. J. Mol. Sci. 22, 4390. doi: https://doi.org/10.3390/ijms22094390 pdf (36MB) (2020: 5,356-IF, Q1-JCR, Q1-SJR) J. Horváthová, R. Moravčík, M. Matúšková, V. Šišovský, A. Boháč, M. Zeman; Inhibition of Glycolysis Suppresses Cell Proliferation and Tumor Progression In Vivo: Perspectives for Chronotherapy
2021 Molecules 26, 2867 (2020: 4.020-IF, Q2-JCR, Q1-SJR) https://doi.org/10.3390/molecules26102867  PDF L. Kovacikova, M. Soltesova-Prnova, M. Majekova, A. Bohac, C. Karasu, M. Stefek Development of Novel Indole;-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications 21/11/21/21/5/21 (10.1.2022)
2021 Bioorganic & Medicinal Chemistry 29 115885  (2020: 3,518-IF, Q2-JCR, Q2-SJR) PDF, https://doi.org/10.1016/j.bmc.2020.115885 M. Hlaváč, L. Kováčiková, M. Šoltésová Prnová, G. Addová, G. Hanquet, M. Štefek, A. Boháč Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket (https://www.sciencedirect.com/science/article/pii/S096808962030715X) 15/14/5/14/5/23/24 (10.1.2022)
2020 J Med Chem 63 369−381 (Reg EVP: 13.01.20) (2019: 5.566-IF, Q1-JCR, Q1-SJR) PDF, M. Hlavac, L. Kovacikova, M. Soltesova Prnova, P. Sramel, G. Addova, M. Majekova, G. Hanquet, A. Bohac, M. Stefek https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01747 Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity 20,10,5,12,12,6,5,20,10
2019 Gen Physiol Biophys 38 157-163 (Reg EVP: MZ-2019) (2018: 1.200-IF, Q4-JCR, Q3-SJR) PDF, J. Horváthová, R. Moravčík, A. Boháč, M. Zeman doi: 10.4149/gpb_2018047 Synergic effects of inhibition of glycolysis and multikinase receptor signalling on proliferation and migration of endothelial cells
2019 Chem Papers 73 71-84 (Reg EVP: 20.2.2019) (2018: 1.132-IF, Q3-JCR, Q2-SJR) PDF, ESM, J. Dobiaš, M. Ondruš, M. Hlaváč, M. Murár, J. Kóňa, G. Addová, A. Boháč (doi: 10.1007/s11696-018-0576-6) Medicinal Chemistry - an effect of a desolvation penalty of an amide group in development of kinase inhibitors(35/5/5/5/5/10/35: 20%CHU) 
2019 Chem Papers 73 55-69 (Reg EVP: 20.2.2019) (2018: 1.132-IF, Q3-JCR, Q2-SJR) PDF, ESM, M. Lácová, M. Čakurda, P. Koiš, G. Addová, A. Boháč (doi: 10.1007/s11696-018-0566-8) A novel and efficient synthesis of 3-aryl-5-(2-hydroxybenzoyl)pyridin-2(1H)-ones by re-cyclization of N-(oxopyranochromenyl)acetamides and their antineoplastic screening(10/35/10/10/35, 20%CHU)
2018 Chem Papers 72 2979-2985 (Reg EVP: 3.10.18), (DOI: 10.1007/s11696-018-0548-x), (2017: 0.871-IF, Q3-JCR, Q2-SJR) PDF, ESM, M. Murár, J. Horvathová, R. Moravčík, G. Addová, M. Zeman, A. Boháč, doi: 10.1007/s11696-018-0548-x Synthesis of glycolysis inhibitor (E)-3-(pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one (3PO) and its inhibition of HUVEC proliferation alone or in a combination with the multi-kinase inhibitor sunitinib(15/15/15/15/15/25, 33%KOCH)
2018 Chem Papers 72 683-690 (2017: 0.871-IF, Q3-JCR, Q2-SJR) PDF, ESM, M. Čakurda, P. Koiš, G. Addová, M. Lácova, A. Boháč doi: 10.1007/s11696-017-0319-0 2H-Pyrano[3,2-c]quinolin-2-ones - their convenient synthesis and selected reactions(30/20/20/10/20, 80%KOCH)
2017 ARKIVOC V, 204–215  (IF 1.048, Q3) PDF, ESM, I. Zemanová, R. Gašparová, A. Boháč, T. Maliar, F. Kraic, G. Addová; (DOI: https://doi.org/10.24820 /ark.5550190.p010.240) Synthesis and antibacterial activity of furo[3,2-b]pyrrole derivatives.
2017 Beilstein J Org Chem 13, 1350–1360 (IF 2.303, Q2) pdf + supp mat or links in BJOCH: PDF + ESM J. Dobiaš, M. Ondruš, G. Addová, A. Boháč; (DOI: 10.3762/bjoc.13.132) Switchable highly regioselective synthesis of 3,4-dihydroquinoxalin-2(1H)ones from o-phenylenediamines and aroylpyruvates
2017 ARKIVOC IV, 184–193  DOI: http://dx.doi.org/10.3998/ark.5550190.p009.788, (IF 1.048, Q3) PDF, I. Zemanová, R. Gašparová, F. Kraic, D. Kružlicová, T. Maliar, A. Boháč, G. Addová, Synthesis of furo[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine derivatives and their antibacterial activity.
2017 Eur J Med Chem 126, 754–761 (DOI: 10.1016/j.ejmech.2016.11.003) link to the paper in EJMECH + PDF + suppl mat + videa (IF 4.816, Q1) M. Murár, J. Dobiaš, P. Šramel, G. Addová, G. Hanquet, A. Boháč; Novel CLK1 Inhibitors Based on N-aryloxazol-2-amine Skeleton - a Possible Way to Dual VEGFR2 TK / CLK Ligands
2017 RCS MedChemComm 8, 81-87 (DOI: 10.1039/c6md00392c, pdf + supplementary info) (IF 2.342, Q3) Deniz Cansen Kahraman, Gilles Hanquet, Loïc Jeanmart, Steve Lanners, Peter Šramel, Andrej Boháč, Rengul Cetin-Atalay; Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells.
2016 Farmaceutický Obzor 85(5-6) 99-112 LINK CASOPIS, PDF CLANKU Základná terminológia vo farmaceutickej a medicínskej chémii, M. Remko, A. Boháč
2016 Cell Commun & Signaling 14:19 (DOI: 10.1186/s12964-016-0142-1, pdf) S.G. Kimani, S. Kumar, V. Davra, Y.-J. Chang, C. Kasikara, K. Geng, W.-I Tsou, S. Wang, M. Hoque, A. Boháč, A. Lewis-Antes, M.S. De Lorenzo, S.V. Kotenko, R.B. Birge; Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase. 
2016 Gen Physiol Biophys 35 511-514 (DOI: 10.4149/gpb_2015055, pdf) R. Moravčík, K. Stebelová, A. Boháč, M. Zeman, Inhibition of VEGF mediated post receptor signalling pathways by recently developed tyrosine kinase inhibitor in comparison with sunitinib
2015 Eur J Med Chem 103 105-122.  DOI:10.1016/j.ejmech.2015.08.012, pdf, suppl mat ) Margaréta Vojtičková, Juraj Dobiaš, Gilles Hanquet, Gabriela Addová, Rengul Cetin-Atalay, Deniz Cansen Yildirim, Andrej Boháč; Ynamide Click chemistry in development of triazole VEGFR2 TK modulators.
2015 J Het Chem 52 425-39, DOI: 10.1002/jhet.2063, pdf, Lucia Lintnerová, Lucia Kováčiková, Gilles Hanquet, Andrej Boháč, Selected Methodologies Convenient for the Synthesis of N,5-Diaryloxazole-2-amine Pharmacophore
2014 Eur J Med Chem 72, 146-159 DOI:10.1016/j.ejmech.2013.11.023, pdf + supplement mat (plachty a spektrá), Lucia Lintnerová, Melissa García-Caballero, Fridrich Gregáň, Milan Melicherčík, Ana R. Quesada, Juraj Dobiaš, Ján Lác, Marta Sališová, Andrej Boháč A development of chimeric VEGFR2 TK inhibitor based on two ligand conformers from PDB: 1Y6A complex - Medicinal chemistry consequences of a TKs analysis (SymAsym, klasifikácia všetkých 34 PDB VEGFR2 TK, objav netradičných DFG-out A-loop opened 1Y6A-like TK konformérov)
2013 Central Eur J Chem 11 502-513 Renata Gašparová, Pavol Koiš, Margita Lácová, Silvia Kováčová, Andrej Boháč Synthesis, reactions and antineoplastic activity of 3-(2-oxo-2H-chromen-3-yl)-2-oxo-2H,5Hpyrano[3,2-c]chromene derivatives
2013 Beilstein J Org Chem 9, 173-179 DOI:10.3762/bjoc.9.20, pdf, M. Murár, G. Addová, A. Boháč; Synthesis of 5-(ethylsulfonyl)-2-methoxyaniline: An important pharmacological fragment of VEGFR2 and other inhibitors.

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1994 Helvetica Chimica Acta 77, 2071-2110 Preparation and Structural Analysis of Several New α,α,α′,α′-Tetraaryl-1,3-dioxolane-4,5-dimethanols (TADDOL's) and TADDOL analogs, their evaluation as titanium ligands in the enantioselective addition of methyltitanium and diethylzinc reagents to benzaldehyde, and refinement of the mechanistic hypothesis. Ito, Y.N., Ariza, X., Beck, A.K., Boháč, A., Ganter, C., Gawley, R.E., Kühnle, F.N.M., Tuleja, J., Wang, Y.M., Seebach, D. Helvetica Chimica Acta 1994 77, 2071-2110. pdf, (https://doi.org/10.1002/hlca.19940770802)


PFIZER - 1st Pfizer Research Award 2009 (Pfizer Lectures 12.11.2009, Conference CENTER,
Radisson Blu CARLTON Hotel, BA)
-----------------------------------------------------------------------------------------------------------some older publications and patents
M. Ilić, J. Ilaš, P. Dunkel, P. Mátyus, A. Boháč, S. Liekens, D. Kikelj, Novel 1,4-benzoxazine and 1,4-benzodioxine inhibitors of angiogenesis, 2012 Eur. J. Med. Chem. 58 160-170.
B. Gabajová, D. Valková, A. Boháč, E. Kováčová, R. Moravčík, M. Zeman; hVEGF165 Expression in Escherichia coli Conserves Its Biological Function 2012 J. of Chem. and Chem. Engineering 6 738-743.
M. Remko, A. Boháč, L. Kováčiková; Molecular structure, pKa, lipophilicity, solubility, absorption, polar surface area, and blood brain barrier penetration of some antiangiogenic agents, 2011 Structural Chem. 22 635-648.
S. Kováčová, L. Kováčiková, M. Lácová, A. Boháč, M. Sališová; Microwave assisted one pot synthesis of 7-substituted 2-(2-oxo-2H-chromen-3-yl)acetic acids as precursors of new anti-tumour compounds 2010 Chemical papers 64 806-811.
M. Lácová, R. Gašparová, P. Koiš, A. Boháč, H. M. El-Shaaer; A facile route to phenyl, phenylsulfanyl and phenylselanyl substituted pyrano[3,2-c]chromenes 2010 Tetrahedron 66 1410-1419.
L. Kováčiková, R. Gašparová, A. Boháč, M. Ďurana, M. Lácová; Synthesis of 3-phenyl-2H,5H-pyrano[3,2-c]chromen-2-one derivatives and their antineoplastic activit, 2010 ARKIVOC 11 188-203.
M. Pažický, V. Semak, B. Gášpár, A. Bílešová, M. Sališová, A. Boháč; Efficient synthesis of 2-alkyl-2-hydroxy-6-X-1-tetralones, 2008 ARKIVOC 8 225-241.
V. Semak, A. Boháč, M. Sališová, G. Addová, P. Danko; Preparation of alpha-methyl-gamma-butyrolactone: Mechanism of its formation and utilization in 2-methyl-1-tetralone synthesis, 2008 Chemical papers 62 275-280.
M. Lácová, H. Stankovičová, A. Boháč, B. Kotzianová, Convenient synthesis and unusual reactivity of 2-oxo-2H,5H-pyrano-[3,2-c]chromenes, 2008 Tetrahedron 64 9646-9653.
A. Almássy, Z. Benková, B. Horváth, A. Boháč; Fluxional behavior of methyl-substituted tricarbonyl(tropone)iron complexes and their different reactivity, 2008 J. of Organometal. Chem. 693 3223-3232.
M. Pažický, B. Gášpár, A. Solladié-Cavallo, M. Sališová, A. Boháč, M. Hutta, G. Addová; The epimerization of chiral alpha-amino acids by 2-hydroxy-2-methyl-1-tetralone template - The synthesis, conditions and mechanism of isomerization, 2006 Synthesis – Stuttgart 12 2013-2018.
V. Langer, D. Gyepesová, P. Mach, E. Scholtzová, B. Gášpár, M. Sališová, A. Boháč; Anti-2-Hydroxy-2-methyl-1-tetralone oxime: X-ray and density functional theory study, 2006 Acta Crystallographica Section C-Crystal Structure Communications 62 o199-o202, URL: http://www.blackwell-synergy.com/doi/full/10.1107/S0108270106005178.
O. Šedý, A. Solladié-Cavallo, M. Sališová, A. Boháč; Organické fosfazénové bázy a ich využitie v organickej chémii 2004 Chemické listy 98 964-969.
L. Soják, G. Addová, R. Kubinec, A. Kraus, A. Boháč; Capillary gas chromatography-mass spectrometry of all 93 acyclic octenes and their identification in fluid catalytic cracked gasoline, 2004 J. of Chromatography A 1025 237-253.
A. Almássy, B. Horváth, A. Boháč, M. Sališová, G. Addová, M. Rosenblum; Thermodynamic and kinetic parameters associated with the fluxional behavior of 2-methyl- and 2,6-dimethyltroponeiron tricarbonylcomplexes 2004 J. of Organometal. Chem. 689 1131-1138.
B. Horváth, A. Boháč, M. Sališová, E. Solčániová, M. Rosenblum; The synthesis of a hydroazulen-2-one skeleton-determination of the diastereoselectivity of [3+2] cycloaddition oftricarbonyl[4,5,6,7-n)-2-methyltropone]iron with E/Z-hapto1-(crotyl)Fp, 2002 J. of Organometal. Chem. 659 43-49.
A. Almássy, M. Pažický, A. Boháč, M. Sališová, G. Addová, M. Rosenblum; Synthesis of 2,6-Dimethyltropone - A New, Convenient Methodology from 2,6-Dimethylcyclohexanone 2002 Synthesis – Stuttgart 12 1695-1700.
G. Addová, L. Soják, R. Kubinec, A. Boháč; The comparison of GC behaviour of acyclic C5-C8 alkenes on squalane and silicone OV-1 stationary phases, 2000 Chemické listy 94 962-963.
R. Kubinec, L. Soják, R. Górová, G. Addová, A. Boháč; The separation of stereoisomers using recycle capillary gas chromatography, 1999 Enantiomer 4 345-350.
A. Boháč, M. Lettrichová, P. Hrnčiar, M. Hutta, Milan; Cyclic beta-diketones - precursors of chiral 1,3-cyclohexadiene iron carbonyl complexes. Ligard exchange - (-)-PPh2(O-HC(Me)-COOEt) - new, chiral, diastereomer-separating ligand in organoiron chemistry, 1996 J. of Organometal. Chem. 507 23-29.
A. Boháč; A transferable gas container (TGC) - improving the balloon inert atmosphere technique, 1995 J. of Chem. Education 72 1995 263-263.
Y. N. Ito, X. Ariza, A. K. Beck, A. Boháč, C. Ganter, R. E. Gawley, F. N. M. Kuhnle, J. Tuleja, Y. M. Wang, D. Seebach; Preparation and structural analysis of several newalpha,alpha,alpha,alpha-tetraaryl-1,3-dioxolane-4,5-dimethanols (TADDOL's) and TADDOL analogs, their evaluation as titanium liganst in the enantioselective addition of methyltitanium and diethylzinc reagents to benzaldehyde, and refinement of the mechanistic hypothesis, 1994 Helvetica Chimica Acta 77 2071-2110.
G. J. Matare, A. Boháč, P. Hrnčiar; Acetylation of beta-Diketone Copper(II) Chelates by Treatment with Ketene 1994 Synthesis – Stuttgart 4 381-382.
A. Boháč, P. Hrnčiar, J. Šraga; Acetylation of 2-acyl-1,3-indandiones with ketene and Determination of the Structure of Products 1992 Chemical papers 46 31-34.
A. Boháč, P. Hrnčiar; 3-Acetoxy-2-cykloalken-1-one by acetylation of cyclic 1,3-diketones with ketene; 1991 Collection of Czechoslovak Chem. Commun. 56 2879-2883.
A. Boháč, P. Hrnčiar; A Convenient Synthesis of 1,3-Diacetoxy-1,3-cycloalkadienes from Cyclic beta-diketones, 1991 Synthesis - Stuttgart. 10 881-882.
A. Boháč, A. Perjéssy, D. Loos, P. Hrnčiar; Elucidation of Acetylation Products of 2-Acyl-1,3-indanediones by Correlation of Infrared Spectral Data, 1991 Monatshefte für Chemie 122 943-948.
Patents:

1. M. Štefek, L. Kováčiková, M. Šoltésová Prnová, G. Addová, A. Boháč; Cemtirestat disulfide, prodrug of aldo-keto reductase inhibitor, preparation, pharmaceutical composition and use thereof. (prvotná prihláška podaná v decembri 2021 PCT/SK2021/050015) 2022 PTC medzinárodná patentová prihláška 50074-2020

2. M. Štefek, L. Kováčiková, M. Šoltésová Prnová, G. Addová, A. Boháč, Zlúčenina cemtirestat disulfid, prekurzor inhibítora aldoketoreduktáz, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom a jeho použitie: 2020 patentová prihláška PP 50074-2020 dátum podania prihlášky: 14.12.2020. Banská Bystrica: Úrad priemyselného vlastníctva Slovenskej republiky, 2020. 25 s.

Lacova, M.; Bohac, A.; Biologically active compounds with pyrano[3,2-c]chromen-2(5H)-one skeleton and a method of their preparation Slovakia (2011), SK 287542 B6 20110104.
Bohac, A.; Snuparek, V.; Varga, I.; Gattnar, O.; Skoda, A.; Manduch, M. Method of production of trans-tramadol and its salts by epimerization of cis-tramadol Slovakia (2004), SK 284181 B6 20041005.
Veverka, M.; Boháč, A.; Almássy, A.; Addová, G.; Varga, I.; Method of preparation of derivatives of substituted 2-arylalkanoic acids by rearrangement of alpha-haloacetophenones and analogs in the presence of orthoformates and acid catalysts Patent No. WO 2004/046080 A1 – Geneva, World Intellectual Property Organization, 2004.
Veverka, M.; Boháč, A.; Križ, M.; Varga, I.; Method of preparation of terfenadine and its derivatives, Patent No. WO2004/043922 A1. Geneva, World Intellectual Property Organization, 2004. ------------------------------------------------------------------------------